Global Dialysis - Mutation points to adenosine as playig a role in arterial calcification.

Mutation points to adenosine as playig a role in arterial calcification.

New Scientist: Currently, only nine individuals are known to have the disorder, dubbed "arterial calcification due to CD73 deficiency". Researchers analysed the DNA of five affected siblings and found that they all had mutations of the NT5E gene, which codes for the CD73 enzyme that produces adenosine - a molecule that helps prevent arteries from calcifying (The New England Journal of Medicine, vol 364, p 432). The findings offer targets for a treatment.

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