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n u o u s + i d e n t i f i c a t i o n + o f + d r u g + t a r g e t s + a n d + p a t h w a y s + t h a t + a r e + a l t e r e d + i n + c a n c e r + i s + n o t + o n l y + c r u c i a l + f o r + o u r + u n d e r s t a n d i n g + o f + c a n c e r + b i o l o g y % 2 c + b u t + a l s o + t o + s e a r c h + f o r + n e w + t a r g e t s + f o r + e a r l y + d i a g n o s i s + a n d + i m p r o v e d + t r e a t m e n t + d e s i g n s + c o n s e q u e n t l y % 2 c + i t + h a s + n e v e r + b e f o r e + b e e n + a s + i m p o r t a n t + t o + r a p i d l y + t r a n s l a t e + s y s t e m s + b i o l o g y + o f + d i s e a s e + a n d + t h e r a p e u t i c s + t o + a c t i o n a b l e + p i p e l i n e + d e c i s i o n s + t o + e n s u r e + t h a t + t h e + o p t i m a l + m a r k e t + c o n d i t i o n s + e x i s t + b y + t h e + t i m e + a + c a n d i d a t e + d r u g + i s + c o m m e r c i a l i z e d f o r + t h i s + r e a s o n + b i o s e e k e r % 2 c + a + l e a d e r + i n + p i p e l i n e + a n a l y t i c s % 2 c + h a s + c o n s t r u c t e d + t h i s + h i g h - l e v e l + d r u g - p a t h w a y + a n a l y z e r + w h i c h + l e t s + y o u + i n t e r a c t + w i t h + t h e + r e n a l + c a n c e r + p i p e l i n e + i n + a + w h o l e + d i f f e r e n t + t h a n + w a y + t h a n + y o u + e v e r + d o n e + b e f o r e + i t s + c a p a b i l i t i e s + m o v e s + y o u + b e y o n d + p o w e r f u l + c o m p e t i t i v e + i n t e l l i g e n c e + t o + a n + o p p o r t u n i t y + s e e k i n g + t o o l + w h i c h + l e t s + y o u % 2 c + b y + m e a n s + o f + b o t h + p r e s e n t + a n d + e m e r g i n g + s c i e n t i f i c + k n o w l e d g e % 2 c + a n a l y z e + t h e + r e n a l + c a n c e r + p i p e l i n e + f o r + i n t e r e s t i n g + c o m p o u n d s + w h i c h + a f f e c t + a n d % 2 f o r + f i t + y o u r + p u r p o s e s % 2 c + m a y + i t + b e + b e n c h m a r k i n g % 2 c + i n % 2 f o u t - l i c e n s i n g % 2 c + c o m b i n a t i o n + t h e r a p y + o p t i o n s % 2 c + d r u g + r e p o s i t i o n i n g % 2 c + i n d i c a t i o n + e x p a n s i o n + e t c y o u + u s e + t h i s + a n a l y z e r + t o o l + i n + r e n a l + c a n c e r + t o % 3 a % 2 a + m a p + t h e + c o m p e t i t i o n + a n d + f i n d + s u i t a b l e + b e n c h m a r k i n g % 2 f l i c e n s i n g + d r u g s + b a s e d + o n + s p e c i f i c + p a t h w a y s + a n d + d r u g + p r o p e r t i e s % 2 a + u n c o v e r + p o t e n t i a l + i n d i c a t i o n + e x p a n s i o n + a r e a s + f o r + y o u r + d r u g + p o r t f o l i o % 2 a + r e v e a l + r e p o s i t i o n i n g + o p p o r t u n i t i e s + f o r + y o u r + o l d e r % 2 c + s h e l v e d + d r u g s % 2 a + e v a l u a t e + t h e + p r o g r e s s i o n + a n d + s u c c e s s + o f + t a r g e t i n g + c e r t a i n + p a t h w a y s + b y + d i f f e r e n t + t u m o r + t y p e s % 2 a + i n v e s t i g a t e + d r u g s + w h i c h + a f f e c t + c r o s s t a l k + b e t w e e n + k e y + p a t h w a y s % 2 a + i n v e s t i g a t e + d i f f e r e n t + c o m b i n a t i o n + t h e r a p y + o p t i o n s + a v a i l a b l e + t o + y o u + i n + v a r i o u s + c a n c e r + t y p e s + u s e + t h i s + t o o l + t o + l o o k + f o r + t h e + m o s t - e f f i c i e n t + w a y s + t o + c o m b i n e + y o u r + d r u g + w i t h + o t h e r + t a r g e t e d + a g e n t s % 2 a + f i n d + p o s s i b l e + a d j u v a n t + t h e r a p y + s e t t i n g s + w i t h + o t h e r + d r u g s t h i s + i s + h o w + y o u + d o + i t % 3 a i n + a n a l y z i n g + d r u g - p a t h w a y + r e l a t i o n s h i p s + t h i s + t o o l + h a s + t h r e e + c o r e + m o d e s % 3 a 1 + s e l e c t + - + y o u + g o + r i g h t + a h e a d + a n d + s e l e c t + a n y + p a t h w a y + f o r + a n a l y s i s 2 + s u g g e s t + - + t h e + t o o l + c a n + s u g g e s t + p a t h w a y s + t o + y o u + a c c o r d i n g + t o + y o u r + p i p e l i n e + s p e c i f i c a t i o n s 3 + c o m p a r e + - + y o u + c a n + o v e r l a y + a n y + p a t h w a y s + w i t h + e a c h + o t h e r + a n d + d o + a + c o m p a r a t i v e + a n a l y s i s y o u + c a n + i n t e r a c t i v e l y + a n a l y z e + a n y + r e n a l + c a n c e r + d r u g - p a t h w a y + r e l a t i o n s h i p + b y + u s i n g + u p + t o + f o u r + d i f f e r e n t + p a t h w a y + s o u r c e s + a n d + f u r t h e r + r e f i n e + y o u r + a n a l y s i s + w i t h + u p + t o + 2 0 + d i f f e r e n t + p i p e l i n e + p a r a m e t e r s % 2 c + i n c l u d i n g + p a r a m e t e r s + s u c h + a s + p r e s e n c e + o f + m u t a t i o n s % 2 c + m o l e c u l a r + f u n c t i o n + o f + t a r g e t s % 2 c + s t a g e + o f + d e v e l o p m e n t % 2 c + s u b - c e l l u l a r + l o c a l i z a t i o n + a n d + m a n y + m o r e + e a c h + p a r a m e t e r + h a s + m u l t i - s e l e c t + o p t i o n s + t o + t h e m + a n d + c a n + b e + u s e d + a s + e i t h e r + a n + i n c l u s i o n + p a r a m e t e r + o r + e x c l u s i o n + p a r a m e t e r u s e r + r e p o r t s + w i t h + g r a p h i c s % 3 a e a c h + a n a l y s i s + r e p o r t + g e n e r a t e d + i n + t h e + d r u g + p a t h w a y + a n a l y z e r + i n c l u d e s + m a n y + d i f f e r e n t + t y p e s + o f + g r a p h s + a n d + t a b l e s + w h i c h + c a n + a l s o + b e + e a s i l y + d o w n l o a d e d + a n d + d r o p p e d + i n t o + a p p l i c a t i o n s + s u c h + a s + p o w e r p o i n t + f o r + e x t e r n a l + p r e s e n t a t i o n s + o u t s i d e + t h e + t o o l t h e + p a t h w a y + a n a l y z e r + c o m e s + i n t e g r a t e d + w i t h + p i p e l i n e + i n f o r m a t i o n w i t h + a + s i m p l e + c l i c k + y o u + c a n + e a s i l y + a n d + q u i c k l y + g e t + r e l e v a n t + i n f o r m a t i o n + a b o u t + t h e + d r u g + b e i n g + i n c l u d e d + i n + a + s p e c i f i c + p a t h w a y + a + t y p i c a l + d r u g + p r o f i l e + r e p o r t s + o n % 2 c + d e p e n d i n g + o n + s t a g e + o f + d e v e l o p m e n t + a n d + a v a i l a b l e + i n f o r m a t i o n % 3 a d r u g + n a m e + % 2 6 + s y n o n y m s p r e s e n t a t i o n + o f + d r u g + n a m e + a n d + s y n o n y m s p r i n c i p a l + c o m p a n y + % 2 6 + p a r t n e r s p r e s e n t a t i o n + o f + p r i n c i p a l + c o m p a n y + a n d + p a r t n e r s + t a r g e t + a n d + m o l e c u l a r + f u n c t i o n + o f + t a r g e t d e s c r i b e d + t a r g e t % 2 8 s % 2 9 + i s % 2 f a r e + p r e s e n t e d + w i t h % 3 a o f f i c i a l + g e n e + s y m b o l + % c 3 % a 2 % c 2 % 8 0 % c 2 % 9 3 + c h r o m o s o m e + l o c a t i o n + % c 3 % a 2 % c 2 % 8 0 % c 2 % 9 3 + g e n e + % 2 6 + p r o t e i n + n a m e + % c 3 % a 2 % c 2 % 8 0 % c 2 % 9 3 + m o l e c u l a r + f u n c t i o n t a r g e t + l o c a l i z a t i o n d e s c r i b e d + t a r g e t % 2 8 s % 2 9 + i s % 2 f a r e + p r e s e n t e d + w i t h + p r i m a r y + a n d + a l t e r n a t e + l o c a l i z a t i o n s t a r g e t + e x p r e s s i o n + p r o f i l e s l i n k s + t o + p r o t e i n + e x p r e s s i o n + p r o f i l e % 2 8 s % 2 9 + o f + t a r g e t % 2 8 s % 2 9 + i n + v a r i o u s + h u m a n + t i s s u e s % 2 c + c e l l + l i n e s + a n d + p r i m a r y + c e l l s % 2 c + i n c l u d i n g + u p + t o % 3 a 4 8 + d i f f e r e n t + n o r m a l + t i s s u e + t y p e s 2 0 + d i f f e r e n t + t y p e s + o f + c a n c e r 4 7 + c e l l + l i n e s 1 2 + s a m p l e s + o f + p r i m a r y + b l o o d + c e l l s m u t a t i o n a l l + t a r g e t s + a r e + c r o s s - r e f e r e n c e d + w i t h + t h e + c a t a l o g u e + o f + s o m a t i c + m u t a t i o n s + i n + c a n c e r + % 2 8 c o s m i c % 2 9 + i t + i s + d e s i g n e d + t o + s t o r e + a n d + d i s p l a y + s o m a t i c + m u t a t i o n + i n f o r m a t i o n + a n d + r e l a t e d + d e t a i l s + a n d + c o n t a i n s + i n f o r m a t i o n + r e l a t i n g + t o + h u m a n + c a n c e r s b i o l o g i c a l + s t r u c t u r e s t h e + i d e n t i t y + o f + a v a i l a b l e + b i o l o g i c a l + s t r u c t u r e s + o n + d r u g + t a r g e t s + w a s + r e t r i e v e d + f r o m + t h e + r c s b + p r o t e i n + d a t a b a n k + f o r + y o u + t o + e a s i l y + r e v i e w + w h a t + a v a i l a b l e + s t r u c t u r e s + o f + d r u g + t a r g e t s + e x i s t t a r g e t e d + p a t h w a y s d e s c r i b e d + t a r g e t % 2 8 s % 2 9 + i s % 2 f a r e + m a t c h e d + f o r + t h e + i n v o l v e m e n t + i n + c e l l u l a r + p a t h w a y s + a c c o r d i n g + t o + b i o c a r t a % 2 c + k e g g % 2 c + n c i - n a t u r e + a n d + n e t p a t h m e c h a n i s m d r u g + m e c h a n i s m + o f + a c t i o n d e v e l o p m e n t a l + p r o j e c t s s u m m a r y + f i e l d + o f + d e v e l o p m e n t a l + p r o j e c t s + f o r + t h e + d r u g % 2 c + i n c l u d i n g + i n d i c a t i o n % 2 c + d e v e l o p m e n t a l + s t a g e + a n d + s t a t u s e x a m p l e % 3 a c a n c e r % 2 c + m y e l o m a + % c 3 % a 2 % c 2 % 8 0 % c 2 % 9 3 + p h a s e + i i + c l i n i c a l + t r i a l + % c 3 % a 2 % c 2 % 8 0 % c 2 % 9 3 + a c t i v e c a n c e r % 2 c + p r o s t a t e + % c 3 % a 2 % c 2 % 8 0 % c 2 % 9 3 + p h a s e + i i i + c l i n i c a l + t r i a l + % c 3 % a 2 % c 2 % 8 0 % c 2 % 9 3 + c e a s e d + d r u g + d e s c r i p t i o n s h o r t + i n t r o d u c t i o n + t o + d r u g c o m p o u n d + d a t a c o m p o u n d + t y p e % 2 c + c h e m i c a l + n a m e % 2 c + c a s + n u m b e r + a n d + m o l e c u l a r + w e i g h t p a t e n t + d a t a a v a i l a b l e + p a t e n t + i n f o r m a t i o n + r e l a t e d + t o + t h e + d r u g + i s + p r e s e n t e d + h e r e f i l l i n g s + a n d + a p p r o v a l s a p p r o v a l s + a n d + s u b m i s s i o n s a n a l y s t + c o m m e n t s d e a l s + % 2 6 + l i c e n s i n g c o l l a b o r a t i o n s + a n d + d e a l s a v a i l a b i l i t y + f o r + l i c e n s i n g p h a s e + i v + d a t a a v a i l a b l e + p h a s e + i v + d e v e l o p m e n t + d a t a % 2 c + d e v e l o p m e n t a l + h i s t o r y + a n d + s c i e n t i f i c + d a t a p h a s e + i i i + d a t a a v a i l a b l e + p h a s e + i i i + d e v e l o p m e n t + d a t a % 2 c + d e v e l o p m e n t a l + h i s t o r y + a n d + s c i e n t i f i c + d a t a p h a s e + i i + d a t a a v a i l a b l e + p h a s e + i i + d e v e l o p m e n t + d a t a % 2 c + d e v e l o p m e n t a l + h i s t o r y + a n d + s c i e n t i f i c + d a t a p h a s e + i + d a t a a v a i l a b l e + p h a s e + i + d e v e l o p m e n t + d a t a % 2 c + d e v e l o p m e n t a l + h i s t o r y + a n d + s c i e n t i f i c + d a t a p h a s e + 0 + d a t a a v a i l a b l e + p h a s e + 0 + d e v e l o p m e n t + d a t a % 2 c + d e v e l o p m e n t a l + h i s t o r y + a n d + s c i e n t i f i c + d a t a p r e c l i n i c a l + d a t a a v a i l a b l e + p r e c l i n i c a l + d e v e l o p m e n t + d a t a % 2 c + d e v e l o p m e n t a l + h i s t o r y + a n d + s c i e n t i f i c + d a t a d i s c o v e r y + d a t a a v a i l a b l e + d i s c o v e r y + d e v e l o p m e n t + d a t a % 2 c + d e v e l o p m e n t a l + h i s t o r y + a n d + s c i e n t i f i c + d a t a s y s t e m + r e q u i r e m e n t s - + o p e r a t i n g + s y s t e m % 3 a + w i n d o w s + % 2 8 2 0 0 0 % 2 f x p % 2 f v i s t a % 2 f 7 % 2 f 8 % 2 9 + a n d + m a c + u s e r s + a r e + o f f e r e d + o n l i n e + a c c e s s + o n l y - + b r o w s e r + a p p l i c 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t o p + p u b l i s h e r s h t t p % 3 a % 2 f % 2 f w w w r e p o r t b u y e r c o m + f o r + m o r e + i n f o r m a t i o n % 3 a + s a r a h + s m i t h + r e s e a r c h + a d v i s o r + a t + r e p o r t b u y e r c o m + e m a i l % 3 a + q u e r y % 4 0 r e p o r t b u y e r c o m + % c 3 % 8 2 % c 2 % a 0 t e l % 3 a + % 2 b 4 4 + 2 0 8 + 8 1 6 + 8 5 + 4 8 + w e b s i t e % 3 a + w w w r e p o r t b u y e r c o m + % 0 a % 0 a % 0 a % 0 a + % 0 9 % 0 9 % 0 9 % 0 9 % 0 9 + + % 0 9 % 0 9 % 0 9 % 0 9 % 0 9 + % 0 9 % 0 9 % 0 9 + + + % 0 9 % 0 9 + + % 0 9 + % 0 9 % 0 9 + + % 0 9 % 0 9 % 0 9 + + + % 0 9 % 0 9 % 0 9 % 0 9 % 0 9 % 0 9 % 0 9 % 0 9 % 0 9 % 0 9 % 0 9 % 0 9 % 0 9 % 0 9 % 0 9 % 0 9 % 0 9 % 0 9 % 0 9 % 0 9 % 0 9 % 0 9 % 0 9 % 0 9 % 0 9 % 0 9 % 0 9 % 0 9 % 0 9 % 0 9 % 0 9 % 0 9 % 0 9 % 0 9 % 0 9 % 0 9 % 0 9 % 0 9 % 0 9 % 0 9 % 0 9 + % 0 9 % 0 9 % 0 9 + + + % 0 9 % 0 9 + + % 0 9 + % 0 9 % 0 9 + + % 0 9 % 0 9 % 0 9 + + + % 0 9 % 0 9 % 0 9 % 0 9 % 0 9 % 0 9 % 0 9 % 0 9 % 0 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